Causes Of Nephrogenic Diabetes Insipidus (NDI)

Causes Of Nephrogenic Diabetes Insipidus (NDI)
Causes Of Nephrogenic Diabetes Insipidus (NDI)

Nephrogenic diabetes insipidus is a rare medical condition. It doesn't come under common diabetes mellitus. Elevated levels of blood sugar are caused by diabetes mellitus. But this particular rare type of diabetes is caused by kidney problems. Kidneys are unable to react to a hormone that controls the balance in fluid. The main results are thirst and frequent urination. This medical condition is not very easy to cure or treat.

Nephrogenic diabetes insipidus: What is it?

This type of diabetes is the result of a hormone named ADH (antidiuretic hormone). This hormone is generated in the hypothalamus a part of the brain. Pituitary gland is the place that stores this hormone. Dehydration or loss of fluid causes the release of this hormone. Kidneys start to retain water when this hormone is generated. This causes collection and decrease of urine.

Enough amount of ADH is generated in nephrogenic diabetes insipidus. But this may not be visible to the kidneys. Normally, ADH sensors of the kidneys are not seen or sometime they might not work well. So, the hormone flows by without any effect. Sufficient water is not absorbed by the kidneys and they release too much of urine as if there is no existence of ADH

Signs of nephrogenic diabetes insipidus

Inability of the kidneys to retain water causes the signs of this type of diabetes and the signs are as follows:

  1. Frequent and excessive urination
  2. Excessive weakness
  3. Pain in muscle
  4. Extreme thirstiness.

When I say extreme thirst you may not feel or understand what it is. People suffering from this medical condition may have to drink water or any other kind of liquid for every fifteen minutes throughout the day. And because your kidneys are not retaining water, you may have to run to the bathroom every now and then.

Conditions that cause nephrogenic diabetes insipidus

This complication affects the ability of the kidneys to reduce the urine. Genes in a family are one of the important causes for this condition and this medical condition is given a name nephrogenic diabetes insipidus. Normally it affects males, but a woman could easily pass this particular gene to her kids. Apart from this you can also get it through other medications that you are taking or other health issues.

Article Source:
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